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Contraindications
Conditions whereby admin of sodium chloride would be detrimental. Not to be used to induce emesis. Sustained release tablets: GI disorders associated with strictures or diverticula.
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Special Precautions
Hypertension, heart failure, peripheral or pulmonary oedema, impaired renal function, liver cirrhosis, preeclampsia. Maintain adequate water intake. Pregnancy. Inj of 3 or 5% sodium chloride solution should be given via a large vein at a rate not exceeding 100 ml/hr. Monitor fluid balance, serum electrolytes and acid base balance espcially during prolonged treatment. Caution when used in patients who are receiving corticosteroids or corticotropin.
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Adverse Reactions
Hypernatraemia; thirst, reduced salivation and lachrymation, fever, tachycardia, hypertension, headache, dizziness, restlessness, irritability and weakness.
Potentially Fatal: Intra-amniotic inj of hypertonic solutions: Disseminated intravascular coagulation, renal necrosis, cervical and uterine lesions, pulmonary embolism, pneumonia and death. |
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Drug Interactions
May affect serum concentrations of lithium.
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ATC Classification
B05XA03 - sodium chloride ; Belongs to the class of electrolyte solutions used in I.V. solutions.
A12CA01 - sodium chloride ; Belongs to the class of sodium-containing preparations. Used as dietary supplements. B05CB01 - sodium chloride ; Belongs to the class of salt solutions used as irrigating solutions. |
